Major

Biology

Degree Name

Bachelor of Arts

Date of Graduation

Spring 2019

Abstract

Osteoinductive therapeutic strategies are essential for the bone healing process and are applicable in multiple orthopaedic procedures. The novel protein Osteoactivin (OA) has proven to stimulate osteoblast differentiation and function in vitro and bone regeneration in vivo in the rat model. More recently, OA has shown significant bone regeneration ability in sheep. The goal of this study is the comparison of osteoactivin with bone morphogenetic protein-2 (BMP-2) in the rat spinal fusion model.

Research Sponsor

Dr. Fayez Safadi

First Reader

Dr. Rolando Ramirez

Second Reader

Dr. James Holda

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