Date of Last Revision
2023-05-03 12:47:53
Major
Biology
Degree Name
Bachelor of Arts
Date of Expected Graduation
Spring 2019
Abstract
Osteoinductive therapeutic strategies are essential for the bone healing process and are applicable in multiple orthopaedic procedures. The novel protein Osteoactivin (OA) has proven to stimulate osteoblast differentiation and function in vitro and bone regeneration in vivo in the rat model. More recently, OA has shown significant bone regeneration ability in sheep. The goal of this study is the comparison of osteoactivin with bone morphogenetic protein-2 (BMP-2) in the rat spinal fusion model.
Research Sponsor
Dr. Fayez Safadi
First Reader
Dr. Rolando Ramirez
Second Reader
Dr. James Holda
Recommended Citation
Ohliger, Andrew, "Effect of Osteoactivin and Bone Morphogenetic Protein-2 on soft tissue in Rat Spinal Fusion Model" (2019). Williams Honors College, Honors Research Projects. 926.
https://ideaexchange.uakron.edu/honors_research_projects/926