Date of Last Revision

2023-05-02 23:40:47


Chemistry - Biochemistry

Degree Name

Bachelor of Science

Date of Expected Graduation

Spring 2017


Flavonoids are highly luminescent compounds that are used in diagnosing and treating certain diseases.They are composed of two aromatic rings (ring A and ring B) and a six-membered heterocyclic pyran ring (ring C) that contains a carbonyl and hydroxyl group, which are responsible for unique photophysical characteristics associated with flavonoids. The target flavonoids (compound 1, or 1, and compound 2 or 2) were synthesized, purified and characterized by NMR spectroscopy. The photophysical properties of the flavonoid were investigated in varying solvents by using UV-vis and fluorescence spectroscopy. Such properties include Excited State Intramolecular Proton Transfer (ESIPT), Intramolecular Charge Transfer (ICT), and solvatochromism. As expected, 1 was more red-shifted than 2 both for absorbance and emission. Compound 1 had the highest fluorescent intensity in toluene whereas 2 had the highest fluorescent intensity in acetonitrile.

Research Sponsor

Dr. Yi Pang

First Reader

Dr. Qin Liu

Second Reader

Dr. Claire Tessier



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