Date of Last Revision
2023-05-02 23:40:47
Major
Chemistry - Biochemistry
Degree Name
Bachelor of Science
Date of Expected Graduation
Spring 2017
Abstract
Flavonoids are highly luminescent compounds that are used in diagnosing and treating certain diseases.They are composed of two aromatic rings (ring A and ring B) and a six-membered heterocyclic pyran ring (ring C) that contains a carbonyl and hydroxyl group, which are responsible for unique photophysical characteristics associated with flavonoids. The target flavonoids (compound 1, or 1, and compound 2 or 2) were synthesized, purified and characterized by NMR spectroscopy. The photophysical properties of the flavonoid were investigated in varying solvents by using UV-vis and fluorescence spectroscopy. Such properties include Excited State Intramolecular Proton Transfer (ESIPT), Intramolecular Charge Transfer (ICT), and solvatochromism. As expected, 1 was more red-shifted than 2 both for absorbance and emission. Compound 1 had the highest fluorescent intensity in toluene whereas 2 had the highest fluorescent intensity in acetonitrile.
Research Sponsor
Dr. Yi Pang
First Reader
Dr. Qin Liu
Second Reader
Dr. Claire Tessier
Recommended Citation
Ingle, Ashley L., "Synthesis and Fluorescent Properties of a New Flavonoid Compound" (2017). Williams Honors College, Honors Research Projects. 469.
https://ideaexchange.uakron.edu/honors_research_projects/469