College

College of Engineering and Polymer Science

Date of Last Revision

2026-05-11 10:13:59

Major

Chemical Engineering

Honors Course

497

Number of Credits

4

Degree Name

Bachelor of Science

Date of Expected Graduation

Spring 2026

Abstract

Clostridioides Difficile (C. diff) is a Anaerobic Gram-positive bacillus that is capable of spore formation, making it difficult to control its spread and duration in clinical environments. This phenomenon can provide danger to first responders, healthcare workers, and patients. The goal of this project is to create a biosensor capable of detecting C. diff in a clinical setting that can be applied to a glove apparatus. The project will involve the use of C. diff aptamers activated on the surface of an electrode. Once surface activation has been verified via surface analysis, the electrodes will be exposed to C. diff and frequency changes will be measured to show detection of the bacteria and analyze sensor sensitivity.

Research Sponsor

Nic Leipzig

First Reader

Christopher Barney

Second Reader

Jeffery Pellegrino

Honors Faculty Advisor

Bi-min Zhang Newby

Proprietary and/or Confidential Information

No

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