"A Form-Fitting Model for the Simulation of Traumatic Brain Injury in Z" by Abigail Armstrong

College

Buchtel College of Arts and Sciences

Date of Last Revision

2025-02-04 13:05:09

Major

Biomedical Science

Honors Course

BIOL 499

Number of Credits

2

Degree Name

Bachelor of Science

Date of Expected Graduation

Spring 2025

Abstract

Developing a model to study traumatic brain injury (TBI) is important as it allows for the better understanding of mechanisms underlying the disease to develop effective treatments and other strategies. Creating a realistic simulation of TBI, permits the research of different types of impacts and severities that can be seen in brain function and structure. The simulation is also valuable for monitoring progression of injuries over time and developing personalized treatment plans. Zebrafish, in particular, are prime candidates given their status as model organisms, affordability, and ease of direct observation in the research setting. Overall, efficient and accurate TBI models are crucial for understanding the complexity of TBI for better diagnostic and treatment protocols to improve the lives of individuals.

Research Sponsor

Brian Bagatto

First Reader

Amber Kerstetter-Fogle

Second Reader

Michelle Evancho-Chapman

Honors Faculty Advisor

Brian Bagatto

Proprietary and/or Confidential Information

No

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