College
Buchtel College of Arts and Sciences
Date of Last Revision
2024-06-04 07:21:52
Major
Biomedical Science
Honors Course
BIOL 499
Number of Credits
2
Degree Name
Bachelor of Arts
Date of Expected Graduation
Spring 2024
Abstract
Understanding the impact of presynaptic and postsynaptic structures on synaptic strength, neurotransmission speed, and morphology is crucial. When cone photoreceptors transmit light-driven signals to cone bipolar cells, various presynaptic structural arrangements can be observed, featuring different numbers of synaptic ribbons. These ribbons facilitate faster initial excitation and sustained transmitter release as vesicles dock at ribbon synapses.
To investigate these structures, I will use the WEBKNOSSOS program to trace dendrites in vertebrate retinal images, determining the number of ribbon synapses and neuron types. This research, building upon the work of Dr. Wan-Qing Yu and Swanstrom, is expected to take about a month. The outcome will be a comprehensive paper outlining the methodology, findings, and implications of identifying neurons based on their synaptic arrangements, ribbons, and dendritic tracings.
This project enhances my college curriculum by providing hands-on research experience, consolidating knowledge in biology and neuroscience, and honing practical skills. It integrates insights into neurotransmission and synaptic functions, contributing to a holistic understanding of neuron function and structure.
Research Sponsor
Jordan Renna
First Reader
Qin Liu
Second Reader
Richard Londraville
Honors Faculty Advisor
Brian Bagatto
Proprietary and/or Confidential Information
No
Recommended Citation
Nguyen, Lauren, "Ribbon Synapses' Role in Synaptic Identification" (2024). Williams Honors College, Honors Research Projects. 1809.
https://ideaexchange.uakron.edu/honors_research_projects/1809