The Affect of DHA Concentration on Lipid Membrane Fluidity

Author

Elise RezabeckFollow

College

Buchtel College of Arts and Sciences

Date of Last Revision

2023-05-06 08:14:02

Major

Biochemistry

Honors Course

3150:497

Number of Credits

2

Degree Name

Bachelor of Science

Date of Expected Graduation

Spring 2023

Abstract

My proposed project will be creating large unilaminar vesicles with varying concentrations of DHA in the vesicles. The diffusion in and out of these vesicles will be tracked by using singular lipid molecules. These singular lipid molecules will be tagged with fluorescence and viewed using an internal reflection fluorescence microscope. The data collected over the course of this project will then be analyzed using Matlab. The result of the project will be to find the specific lipid diffusion constant of these unilaminar vesicles. The relationship between the concentration of DHA and lipid diffusion and membrane fluidity will be found as well.

Research Sponsor

Dr. Chunming Liu

First Reader

Shuzhen Liu

Second Reader

Kai Gu

Honors Faculty Advisor

Dr. William Donovan

Proprietary and/or Confidential Information

Yes

Recommended Citation

Rezabeck, Elise, "The Affect of DHA Concentration on Lipid Membrane Fluidity" (2023). Williams Honors College, Honors Research Projects. 1637.
https://ideaexchange.uakron.edu/honors_research_projects/1637