College
Buchtel College of Arts and Sciences (BCAS)
Date of Last Revision
2023-05-03 18:28:23
Major
Biology
Honors Course
3100-499-002
Number of Credits
2
Degree Name
Bachelor of Science
Date of Expected Graduation
Spring 2020
Abstract
There are many fish that can withstand hypoxia levels. One in particular is the zebrafish (Danio rerio). The zebrafish is a small-sized, Cyprinid teleost fish, and has been used in a laboratory setting for many reasons. A few reasons being that they are widely available, easy to care for, and the cost for these fish are very low. There are various reasons why these fish are used as a model. One main reason is because their cardiovascular system is one of the first developing organs. This allows for better resolution when studying the cardiovascular system. The purpose of this study is to investigate the cardiovascular system of danio rerio during low oxygen conditions, and to investigate the cardiac response when Pcrit is reached. It is hypothesized that cardiac response will increase during the hypoxic conditions. This is because acute bouts of hypoxia are more stressful and cause more physiological impairment, than low O2 environments. A response will be much more apparent in embryonic zebrafish in stressful conditions. This stress response will be seen when normal heart rate, cardiac output, and stroke volume change.
Research Sponsor
Dr. Brian Bagatto
First Reader
Dr. Qin Liu
Second Reader
Dr. Rolando Ramirez
Honors Faculty Advisor
Dr. Brian Bagatto
Recommended Citation
Fetterman, Bryce, "The Cardiovascular Response to Acute Hypoxic Conditions in Danio rerio" (2020). Williams Honors College, Honors Research Projects. 1133.
https://ideaexchange.uakron.edu/honors_research_projects/1133
Included in
Aquaculture and Fisheries Commons, Behavior and Ethology Commons, Comparative and Evolutionary Physiology Commons, Laboratory and Basic Science Research Commons, Other Ecology and Evolutionary Biology Commons, Terrestrial and Aquatic Ecology Commons