Date of Graduation

Spring 2017

Document Type

Honors Research Project

Degree Name

Bachelor of Science

Major

Chemistry - Biochemistry

Research Sponsor

Dr. Yi Pang

First Reader

Dr. Qin Liu

Second Reader

Dr. Claire Tessier

Abstract

Flavonoids are highly luminescent compounds that are used in diagnosing and treating certain diseases.They are composed of two aromatic rings (ring A and ring B) and a six-membered heterocyclic pyran ring (ring C) that contains a carbonyl and hydroxyl group, which are responsible for unique photophysical characteristics associated with flavonoids. The target flavonoids (compound 1, or 1, and compound 2 or 2) were synthesized, purified and characterized by NMR spectroscopy. The photophysical properties of the flavonoid were investigated in varying solvents by using UV-vis and fluorescence spectroscopy. Such properties include Excited State Intramolecular Proton Transfer (ESIPT), Intramolecular Charge Transfer (ICT), and solvatochromism. As expected, 1 was more red-shifted than 2 both for absorbance and emission. Compound 1 had the highest fluorescent intensity in toluene whereas 2 had the highest fluorescent intensity in acetonitrile.

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