"Drug Eluting Electrospun Rubbery Fiber Mats" by Aditya Jindal, Andrea A. Charif et al.
 

Polymer Science Faculty Research

Title

Drug Eluting Electrospun Rubbery Fiber Mats

Document Type

Conference Proceeding

Publication Date

Spring 3-16-2014

Abstract

This work reports release studies of acetylsalicylic acid (Aspirin), a model drug from electrospun ArbomatrixTM {a block copolymer with arborescent polyisobutylene (PIB) core and poly (para-methyl styrene) PMS end blocks} polymer fiber mats. ArbomatrixTM –PEG polymer solutions containing 15 and 30 wt% Aspirin were electrospun onto parchment paper to yield free-standing rubbery fiber mats. Aspirin release into phosphate buffered saline (PBS) solution (pH = 7.4) at 37oC was measured by UV spectroscopy. In three days 42 and 90% of the loaded Aspirin was released from the mats containing 15 and 30wt% Aspirin, respectively. Due to the excellent biocompatibility of ArbomatrixTM these mats hold great promise for drug delivery applications.

Publication Title

Abstracts of Papers of the American Chemical Society

Volume

247

Issue

301-pmse

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