Buchtel College of Arts and Sciences

Date of Last Revision

2023-05-08 15:50:40


Biomedical Science

Honors Course

BIOL 499-002

Number of Credits


Degree Name

Bachelor of Science

Date of Expected Graduation

Spring 2023


The use of electronic cigarettes, commonly referred to as e-cigarettes or vapes, has increased exponentially in recent years despite the lack of research into potentially negative physiological effects. The rise in e-cigarette use is likely due to the overwhelming evidence regarding the addictive properties of nicotine and the damage caused by traditional tobacco cigarettes. Most e-cigarettes, however, still contain nicotine and are associated with a rise in nicotine-related intoxications (Belkoniene et al., 2019). There are nicotine-free e-cigarette options, which are gaining popularity, but it is unknown if they carry similar or other negative physiological effects. Studies involving e-cigarettes containing nicotine show that inhalation increases whole-body metabolic rate, yet studies including nicotine-free e-cigarettes are currently lacking (Olfert et al., 2018). This project intended to investigate any differences in maximal metabolic rate (MMR) following an acute exposure period to water with dissolved e-cigarette vapors; with the hypothesis that both nicotine and nicotine-free vapor will increase MMR. The Louisiana crayfish, Procambrus clarkii, was the organism studied due to availability and their low maintenance requirement. E-cigarette vapor did not have a statistically significant effect on MMR between treatment groups or with the control group.

Research Sponsor

Brian Bagatto

First Reader

Jordan Renna

Second Reader

David Modarelli

Honors Faculty Advisor

Brian Bagatto

Proprietary and/or Confidential Information




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