College
Buchtel College of Arts and Sciences
Date of Last Revision
2023-05-04 21:56:36
Major
Biology
Honors Course
3100:499
Number of Credits
3
Degree Name
Bachelor of Science
Date of Expected Graduation
Spring 2022
Abstract
Melanopsin ganglion cells are intrinsically photosensitive ganglion cells in the mammalian retina. These cells mediate aspects of non-image forming vision to help regular circadian rhythm. Glaucoma is an eye disease involving an increase in intraocular pressure that has been linked to irregular circadian rhythm. This project will investigate the impact glaucoma has on these melanopsin ganglion cells at different pathological timepoints. This will be performed by using dissection, immunohistochemistry, and computer imaging methods to visualize, trace, and measure the cells’ morphologies in both control and glaucomatous retinas at different timepoints of disease to analyze if glaucoma has a significant effect on the cells.
Research Sponsor
Jordan M. Renna
First Reader
Qin Liu
Second Reader
Rolando J. J. Ramirez
Honors Faculty Advisor
Brian Bagatto
Recommended Citation
Keenan, Kristin, "Glaucoma Alters the Morphology of Mouse Melanopsin-Containing Retinal Ganglion Cells" (2022). Williams Honors College, Honors Research Projects. 1503.
https://ideaexchange.uakron.edu/honors_research_projects/1503
Cover sheet with signatures
KeenanHonorsSignaturesFinal.pdf (179 kB)
Final Manuscript Signatures