College

Buchtel College of Arts and Sciences (BCAS)

Date of Last Revision

2020-05-08 12:33:46

Major

Biology

Honors Course

3100 499

Number of Credits

3

Degree Name

Bachelor of Science

Date of Expected Graduation

Spring 2020

Abstract

Preeclampsia is a hypertensive disorder of pregnancy that leads to a multitude of problems for the mother and fetus during and after pregnancy. While the effects on the mother's body after pregnancy are often overlooked, preeclamptic mothers are prone to cardiovascular diseases from the great deal of stress experienced through the duration of a preeclamptic pregnancy. The associated high blood pressure causes cardiac muscle to work a great deal harder in an attempt to successfully perfuse tissues adequately. This increase in prolonged stress leads to remodeling of the cardiovascular tissues-significantly increasing the risk of heart issues in life beyond the term of the preeclamptic pregnancy. Efforts to improve cardiac oxidative stress via Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) treatment are analyzed in this study.

Research Sponsor

Dr. Rolando Ramirez

First Reader

Dr. David Modarelli

Second Reader

Dr. Robert Duff

Honors Faculty Advisor

Dr. Brian Bagatto

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