Date of Last Revision
2023-05-02 14:15:18
Major
Chemistry
Degree Name
Bachelor of Science
Date of Expected Graduation
Spring 2015
Abstract
A series of N,N’-bis(arylmethyl)benzimidazolium salts with hydrophilic and lipophilic substituents have been synthesized, characterized, and tested against select non-small cell cancer cell lines. Substituent variations on the imidazole ring have shown that lipophilicity and hydrophilicity can influence the imidazolium salts’ anti-proliferative activity and aqueous solubility.
Research Sponsor
Dr. Wiley J. Youngs
First Reader
Dr. Michael Konopka
Second Reader
Dr. Matthew J. Panzner
Recommended Citation
Williams, Travis M., "Synthesis and Anti-Proliferative Activity of N,N’-bis(arylmethyl)benzimidazolium Salts" (2015). Williams Honors College, Honors Research Projects. 66.
https://ideaexchange.uakron.edu/honors_research_projects/66