Date of Last Revision
2023-05-02 14:17:54
Major
Chemistry
Degree Name
Bachelor of Science
Date of Expected Graduation
Spring 2015
Abstract
Various ions of poly-L-lysine and polystyrene sulfonic acid were successfully observed first within a matrix-assisted laser desorption/ionization mass spectrometer and subsequently in an electrospray ionization mass spectrometer. The successful ionization of these polymers allowed for studies to be performed on the noncovalent interactions between the two. Noncovalent interactions were effectively studied on both instruments, but further quantified using tandem mass spectrometry found within the MALDI system and ion-mobility mass spectrometry found within the electrospray ionization system. As a result of employing the use of ion-mobility, various different stoichiometries and charges of polyelectrolyte complexes could be distinguished.
Research Sponsor
Chrys Wesdemiotis
First Reader
Christopher Ziegler
Second Reader
Matthew Panzner
Recommended Citation
Marino, Anthony J., "Characterization of Noncovalent Complexes of Polyelectrolytes by Mass Spectrometry" (2015). Williams Honors College, Honors Research Projects. 166.
https://ideaexchange.uakron.edu/honors_research_projects/166
Figures included in Honors Project