Polymer Science Faculty Research
Title
Identification of a Highly Specific Hydroxyapatite-binding Peptide using Phage Display
Document Type
Article
Publication Date
5-15-2008
Abstract
A peptide sequence SVSVGMKPSPRP that selectively recognizes hydroxyapatite (HA) is identified by using a phage display approach. The engineered sequence exhibits chemical and structural specificity for HA over calcium carbonate and HA's amorphous calcium phosphate precursor. In situ binding to HA in a tooth cross section further demonstrates the sequence specificity and utility in nondestructive imaging applications.
Publication Title
Advanced Materials
Volume
20
Issue
10
First Page
1830
Last Page
1836
Recommended Citation
Roy, Marc D.; Stanley, Scott K.; Amis, Eric J.; and Becker, Matthew, "Identification of a Highly Specific Hydroxyapatite-binding Peptide using Phage Display" (2008). Polymer Science Faculty Research. 171.
https://ideaexchange.uakron.edu/polymerscience_ideas/171