Major

Biology

Degree Name

Bachelor of Science

Date of Graduation

Spring 2016

Abstract

Four groups of experimental mice are studied in this experiment following intentional exposure to murine norovirus (MNV). Two groups are exposed to the virus at different points in their lives, and the other two are not infected and studied alongside the other groups as controls.

Past research has indicated that B and T immune cells are not essential to MNV resistance. Additionally, antibody production against MNV has shown to be slow as infection progresses. Thus, the expected results from the experiment are that the mice with longer infections of MNV will have larger quantities of IgG than those more recently infected with the virus. Immunological data gathered from these groups is compared to IgG counts from control mice, which are comprised of pathologically clean mice of the same strain as the sentinel mice infected with MNV and the same strain as the colony with innate exposure to MNV.

Research Sponsor

Dr. Rolando Ramirez

First Reader

Dr. Jordan Renna

Second Reader

Kelly Stevanov

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.