Buchtel College of Arts and Sciences

Date of Last Revision

2023-05-08 17:26:51


Biomedical Science

Honors Course

Honors Research Project

Number of Credits


Degree Name

Bachelor of Science

Date of Expected Graduation

Spring 2023


Preeclampsia is a complication of pregnancy, where the placenta lacks sufficient blood flow due to abnormal formation of the vascular endothelial cells. This results in hypertension and increased reactive oxygen species, causing oxidative stress. The VEGF (vascular endothelial growth factor) helps develop new growth, so by increasing the receptors VEGFR2 by injection of LTP nanoparticles into the uterine wall of RUPP rats, one can see if there would be improvement in the otherwise reduced uterine pressure pregnant rat. This would be confirmed by the 8-isoprostane test, which measures oxidative stress.

Research Sponsor

Dr. Rolando JJ Ramirez

First Reader

Dr. Henry Astley

Second Reader

Dr. M Rumman Hossain

Honors Faculty Advisor

Dr. Brian Bagatto

Proprietary and/or Confidential Information




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