College of Engineering (COE)

Date of Last Revision

2020-05-05 05:34:49


Biomedical Engineering - Biomaterials and Tissue Engineering

Honors Course

4800:491, 4800:492

Number of Credits


Degree Name

Bachelor of Science

Date of Expected Graduation

Spring 2020


Pediatric patients with disorders and diseases of the heart have limited options with regards to implantable devices. Many of these implants are ventricular assist devices, which is not always suitable for a patient. Total artificial hearts (TAHs) have supported many adult patients until transplantation, and we believe that they could do the same for pediatric patients. SynCardia has the only Food and Drug Administration (FDA) approved TAH devices. Since SynCardia is the only company with FDA approved TAHs, we decided to modify the design of the SynCardia TAH for use in pediatric patients without compromising the function of the current device. This paper reports on the process for the design modification to the TAH. The project resulted in detailed drawings of our proposed device, a risk mitigation summary, and a partial verification report.

Research Sponsor

Dr. Ge Zhang

First Reader

Dr. Rebecca Kuntz Willits

Second Reader

Dr. Lawrence Noble

Honors Faculty Advisor

Dr. Lawrence Noble

Clark_Marks_Signature_Page.pdf (14 kB)
Signature Page



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