Polymer Science Faculty Research


Precise Functionalization of Polymers Using CALB-Based Enzymatic Methods

Document Type

Conference Proceeding

Publication Date

Spring 3-16-2014


The synthesis of functional polymers with well-defined structure, end-group fidelity and physico-chemical properties useful for biomedical applications has proven challenging. Chemo-enzymatic methods are an alternative strategy to increase the diversity of functional groups in polymeric materials. Specifically, enzyme-catalyzed polymer functionalization carried out under solventless conditions is a great advancement in the design of green processes for biomedical applications, where the toxicity of solvents and catalyst residues need to be considered. Enzymes offer several distinct advantages, including high efficiency, catalyst recyclability, and mild reaction conditions.

Publication Title

Abstracts of Papers of the American Chemical Society