Spinal Subarachnoid Space Pressure Measurements in an in Vitro Spinal Stenosis Model: Implications on Syringomyelia Theories
Full explanation for the pathogenesis of syringomyelia (SM), a neuropathology characterized by the formation of a cystic cavity (syrinx) in the spinal cord (SC), has not yet been provided. It has been hypothesized that abnormal cerebrospinal fluid (CSF) pressure, caused by subarachnoid space (SAS) flow blockage (stenosis), is an underlying cause of syrinx formation and subsequent pain in the patient.
Journal of Biomechanical Engineering
Martin, Bryn A.; Labuda, Richard; Royston, Thomas J.; Oshinski, John N.; Iskandar, Bermans; and Loth, Francis, "Spinal Subarachnoid Space Pressure Measurements in an in Vitro Spinal Stenosis Model: Implications on Syringomyelia Theories" (2010). Mechanical Engineering Faculty Research. 420.