College
Buchtel College of Arts and Sciences (BCAS)
Date of Last Revision
2023-05-03 17:32:48
Major
Biology
Honors Course
3100 499
Number of Credits
3
Degree Name
Bachelor of Science
Date of Expected Graduation
Spring 2020
Abstract
Preeclampsia is a hypertensive disorder of pregnancy that leads to a multitude of problems for the mother and fetus during and after pregnancy. While the effects on the mother's body after pregnancy are often overlooked, preeclamptic mothers are prone to cardiovascular diseases from the great deal of stress experienced through the duration of a preeclamptic pregnancy. The associated high blood pressure causes cardiac muscle to work a great deal harder in an attempt to successfully perfuse tissues adequately. This increase in prolonged stress leads to remodeling of the cardiovascular tissues-significantly increasing the risk of heart issues in life beyond the term of the preeclamptic pregnancy. Efforts to improve cardiac oxidative stress via Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) treatment are analyzed in this study.
Research Sponsor
Dr. Rolando Ramirez
First Reader
Dr. David Modarelli
Second Reader
Dr. Robert Duff
Honors Faculty Advisor
Dr. Brian Bagatto
Recommended Citation
Metz, Rachel, "Cardiovascular Tissue Remodeling of Preeclampsia" (2020). Williams Honors College, Honors Research Projects. 1178.
https://ideaexchange.uakron.edu/honors_research_projects/1178
Included in
Cardiovascular Diseases Commons, Female Urogenital Diseases and Pregnancy Complications Commons