Atomic Force Microscopic and Encrustation Studies of Novel Prospective Polyisobutylene-based Thermoplastic Elastomeric Biomaterials
This paper investigates the surface morphology of polyisobutylene–polystyrene (PIB–PS) block-type thermoplastic elastomers, emerging new biomaterials, by atomic force microscopy (AFM). A novel aborescent PIB–PS block polymer (AR15) was synthesized through inimer-type living carbocationic polymerization and characterized in comparison with a semi-commercial PIB–PS thermoplastic elastomer (TPE) (TS30). Tapping-mode AFM revealed that PS spheres with a domain size of 45–60 nm were very irregularly distributed in the continuous PIB phase of the aborescent AR15 polymer, whereas ordered and mixed cylindrical/lamellar morphology with 25–31 nm hard phase appeared in a linear TS30 triblock polymer. Moreover, AFM revealed rough surface features of a 1 mm thick compression molded TS30 polymer disk coated with a probiotic protein. AR15 disks were used for in vivo urinary tract encrustation study. Encrustation of the PIB–PS disks was comparable or better than that of medical-grade silicone rubber. The preliminary results imply the prospect of PIB–PS thermoplastic elastomers as emerging soft biomaterials. Copyright © 2003 John Wiley & Sons, Ltd.
Polymers for Advanced Technologies
Puskas, Judit; Chen, Yaohong; Antony, Prince; Kwon, Yongmoon; Kovar, Milan; Harbottle, Robert R.; Jong, Kathy De; Norton, Peter R.; Cadieux, Peter; Burton, Jeremy; Reid, Gregor; Beiko, Darren; Watterson, James D.; and Denstedt, John, "Atomic Force Microscopic and Encrustation Studies of Novel Prospective Polyisobutylene-based Thermoplastic Elastomeric Biomaterials" (2004). Chemical and Biomolecular Engineering Faculty Research. 469.