Background: Cadherins are cell surface adhesion molecules that play important roles in development of vertebrate tissues and organs. We studied cadherin2 expression in developing zebrafish heart using in situ hybridization and immunocytochemical methods, and we found that cadherin2 was strongly expressed by the myocardium of the embryonic zebrafish. To gain insight into cadherin2 role in the formation and function of the heart, we analyzed cardiac differentiation and performance in a cadherin2 mutant, glass onion (glo).
BMC Developmental Biology
Bagatto, Brian; Francl, Jessie; Liu, Bei; and Liu, Qin, "Cadherin2 (N-Cadherin) Plays An Essential Role in Zebrafish Cardiovascular Development" (2006). Biology Faculty Research. 9.